Efficacy of High and Low-Dose Simvastatin on Vascular Oxidative Stress and Neurological Outcome in Patients With AIS

PHASE3CompletedINTERVENTIONAL
Enrollment

64

Participants

Timeline

Start Date

April 1, 2014

Primary Completion Date

October 4, 2014

Study Completion Date

December 31, 2015

Conditions
Ischemic Stroke
Interventions
DRUG

Simvastatin 10 mg

"Simvastatin is a cholesterol-lowering medication that blocks the production of cholesterol (a type of fat) in the body.~Simvastatin reduces low-density lipoprotein (LDL) cholesterol and total cholesterol in the blood. Lowering your cholesterol can help prevent heart disease and hardening of the arteries, conditions that can lead to heart attack, stroke, and vascular disease."

DRUG

Simvastatin 40 mg

"Simvastatin is a cholesterol-lowering medication that blocks the production of cholesterol (a type of fat) in the body.~Simvastatin reduces low-density lipoprotein (LDL) cholesterol and total cholesterol in the blood. Lowering your cholesterol can help prevent heart disease and hardening of the arteries, conditions that can lead to heart attack, stroke, and vascular disease."

All Listed Sponsors
lead

Thammasat University

OTHER

NCT03402204 - Efficacy of High and Low-Dose Simvastatin on Vascular Oxidative Stress and Neurological Outcome in Patients With AIS | Biotech Hunter | Biotech Hunter