Investigation of the Safety and Pharmacology of Dry Powder Inhalation of Treprostinil

PHASE3CompletedINTERVENTIONAL
Enrollment

121

Participants

Timeline

Start Date

January 2, 2018

Primary Completion Date

May 6, 2019

Study Completion Date

November 25, 2019

Conditions
Primary Pulmonary Hypertension
Interventions
DRUG

LIQ861 Inhaled Treprostinil

LIQ861 bulk powder is generated from a treprostinil/excipient matrix from which particles of precise size and shape are created and filled into a hydroxypropyl methylcellulose (HPMC) capsule (size 3). LIQ861 capsules are provided in capsule strengths of 25 μg, 50 μg, 75 μg and 100 μg treprostinil.

Trial Locations (38)

10279

NYU Langone Health, New York

11501

NYU Winthrop University Hospital, Mineola

15212

Alleghany General Hospital, Pittsburgh

15213

UPMC Presbyterian Hospital, Pittsburgh

19104

University of Pennsylvania Health System, Philadelphia

22042

INOVA Fairfax Medical Campus, Falls Church

27599

University of North Carolina School of Medicine, Chapel Hill

30060

Wellstar Research Institute, Marietta

30322

Emory University School of Medicine, Atlanta

32224

Mayo Clinic-Jacksonville, Jacksonville

32610

University of Florida, Gainesville

32803

AdventHealth, Orlando

40202

Kentuckiana Pulmonary Research Center, Louisville

43210

the Ohio State University Wexner Medical Center, Columbus

44106

University Hospitals of Cleveland Medical Center, Cleveland

44195

Cleveland Clinic, Cleveland

45267

University of Cincinnati Medical Center, Cincinnati

53226

The Medical College of Wisconsin/Froedtert Hospital, Milwaukee

55435

University of Minnesota, Minneapolis

55905

Mayo Clinic-Rochester, Rochester

60611

Northwestern Medicine, Feinberg School of Medicine, Chicago

60637

University of Chicago Medicine, Chicago

63110

Washington University School of Medicine, St Louis

66103

University of Kansas Medical Center, Kansas City

70121

Ochsner Medical Center, New Orleans

75390

UT Southwestern Medical Center, Dallas

77030

Houston Methodist Lung Center, Houston

University of Texas - Health Science Center, Houston

78229

University of Texas Health Science Center at San Antonio, San Antonio

80045

University of Colorado Anschutz Medical Campus, Aurora

85006

Banner University Medical Center, Phoenix

85012

Arizona Pulmonary Specialists, Ltd., Phoenix

87106

University of New Mexico Health Science Center, Albuquerque

90073

West Los Angeles VA Healthcare Center, Los Angeles

90502

Los Angeles Biomedical Research Center, Torrance

95817

UC Davis Medical Center, Sacramento

97239

Oregon Health and Science Center, Portland

02111

Tufts Medical Center, Boston

Sponsors
All Listed Sponsors
collaborator

Nuventra, Inc.

INDUSTRY

lead

Liquidia Technologies, Inc.

INDUSTRY

NCT03399604 - Investigation of the Safety and Pharmacology of Dry Powder Inhalation of Treprostinil | Biotech Hunter | Biotech Hunter