NCT03395587 - Efficiency of Vaccination with Lysate-loaded Dendritic Cells in Patients with Newly Diagnosed Glioblastoma | Biotech Hunter

Enrollment

136

Participants

Timeline

Start Date

March 6, 2018

Primary Completion Date

May 31, 2027

Study Completion Date

May 31, 2027

Conditions

Glioblastoma

Interventions

BIOLOGICAL

Autologous, tumor lysate-loaded, mature dendritic cells (DC)

Advanced therapy medicinal product (ATMP) produced at the University Hospital Düsseldorf according to Good Manufacturing Practice (GMP) with production permission according §13 AMG (German Drug Law) of the local authorities (Bezirks¬regierung Düsseldorf)

DRUG

standard therapy

temozolomide, fractionated radiochemotherapy

Trial Locations (6)

40225

Neurochirurgische Klinik, Universitätsklinikum Düsseldorf, Düsseldorf

44534

St. Marien Hospital Lünen, Klinik für Neurochirurgie, Lünen

44829

Klinik für Neurologie, Knappschaftskrankenhaus Bochum, Bochum

47055

Klinik für Neurochirurgie, Sana Kliniken Duisburg, Duisburg

47805

Helios Klinikum Krefeld, Klinik für Neurochirurgie, Krefeld

48149

Klinik für Allgemeine Neurologie, Universitätsklinikum Münster, Münster

All Listed Sponsors

collaborator

German Federal Ministry of Education and Research

OTHER_GOV

lead

Heinrich-Heine University, Duesseldorf

OTHER