Study of IMNN-001 (Also Known as GEN-1) With NACT for Treatment of Ovarian Cancer (OVATION 2)

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

130

Participants

Timeline

Start Date

September 5, 2018

Primary Completion Date

July 25, 2024

Study Completion Date

November 30, 2025

Conditions
Epithelial Ovarian CancerFallopian Tube CancerPrimary Peritoneal Cancer
Interventions
BIOLOGICAL

IMNN-001

IL-12 Plasmid Formulated with PEG-PEI-Cholesterol Lipopolymer

DRUG

Carboplatin

AUC 6 IV over 1 hour on Day 1 of each cycle

DRUG

Paclitaxel

175 mg/m2 IV over 3 hours on Day 1 of each cycle

Trial Locations (21)

10016

NYU Langone, New York

11042

Monter Cancer Center, Lake Success

11501

NYU Langone, Long Island, Mineola

32803

Advent Health, Orlando

33701

Women's Care Florida, St. Petersburg

35233

University of Alabama Birmingham, Birmingham

36604

Mitchell Cancer Institute (University of South Alabama), Mobile

37403

Chattanooga Women's Health, Chattanooga

38138

The West Clinic, Germantown

53226

Medical College of Wisconsin, Milwaukee

57104

Sanford Health, Sioux Falls

63110

Washington University School of Medicine in St. Louis, St Louis

73104

Stephenson Cancer Center - Oklahoma University, Oklahoma City

90603

Innovative Clinical Research, Whittier

92663

Gynecologic Oncology Associates (Hoag Hospital), Newport Beach

97213

Providence Cancer Institute, Portland

99204

Providence Health Care, Spokane

02114

Massachusetts General Hospital, Boston

08105

MD Anderson at Cooper, Camden

07601

Hackensack University Medical Center, Hackensack

H2X 0A9

CHUM, Montreal

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Imunon

INDUSTRY