30
Participants
Start Date
January 17, 2018
Primary Completion Date
December 29, 2023
Study Completion Date
December 8, 2025
Prostate bed with integrated boost
Radiation will be delivered at an escalated dose to areas of recurrent prostate cancer identified on imaging and a reduced dose will be delivered to the entire prostate bed.
Prostate bed irradiation only
Radiation will be delivered to the prostate bed only.
Whole Body Bone Scan
At screening, if required by clinician.
18F-NaF PET Imaging
At screening, if required by clinician.
CT
Computed tomography of the abdomen and pelvis if clinically indicated at screening, with oral and intravenous contrast.
mpMRI
mpMRI of the prostate bed at screening and 6 month follow up.
ADT
After enrollment if clinically indicated (i.e., anti-androgen, gonadotropin releasing hormone agonist, or combination of both).
National Institutes of Health Clinical Center, Bethesda
National Cancer Institute (NCI)
NIH