4
Participants
Start Date
January 17, 2018
Primary Completion Date
October 16, 2019
Study Completion Date
October 16, 2019
Tacrolimus Extended Release Oral Tablet [Envarsus]
Switching from current version of tacrolimus to the extended release, once a day version (Envarsus) and titrating dose to achieve an optimal trough level. Goal trough tac level \> 8 ng/ml, MPA at 720 mg bid unless medically contraindicated, prednisone at current dose (5mg) or continue taper to 5mg per center standard of care protocol.
Plasma Exchange and IVIG (Intravenous Immunoglobulin )
Plasma exchange x 5 treatments, each followed by IVIG 200 mg/kg except last dose of 1 gm/kg. Rituximab 375 mg/m2 following final plasma exchange treatment.
University of Colorado Anschutz Medical Campus, Aurora
Collaborators (1)
Veloxis Pharmaceuticals
INDUSTRY
University of Colorado, Denver
OTHER