Combined Therapy of Nivolumab and Adoptive T Cell Therapy in Metastatic Melanoma Patients

PHASE1/PHASE2UnknownINTERVENTIONAL
Enrollment

11

Participants

Timeline

Start Date

February 12, 2018

Primary Completion Date

January 31, 2024

Study Completion Date

January 31, 2024

Conditions
Melanoma
Interventions
DRUG

TIL + IL-2 + Nivolumab

"The patients will receive Nivolumab (at a dose of 3 mg per kilogram of body weight) every 2 weeks from day0 until week52.~Two TIL (Tumor Infiltrating Lymphocytes) injections will be performed: at week 14 and at week 18.~The TIL injections are systematically followed by subcutaneous injections of Proleukin® (IL-2) at a concentration of 6 million international unit (IU) per day for 5 days."

Trial Locations (1)

44000

RECRUITING

Nantes University Hospital, Nantes

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

lead

Nantes University Hospital

OTHER

NCT03374839 - Combined Therapy of Nivolumab and Adoptive T Cell Therapy in Metastatic Melanoma Patients | Biotech Hunter | Biotech Hunter