202
Participants
Start Date
November 1, 2017
Primary Completion Date
June 24, 2018
Study Completion Date
November 30, 2020
BioGlue Surgical Adhesive
BioGlue (produced by CryoLife in Kennesaw, GA) is a surgical adhesive with two components respectively purified bovine serum albumin (BSA) and Glutaraldehyde (their proportions are 4:1). Crosslinked bonds (covalent bonds) of Glutaraldehyde cross-link the protein on the surface of the tissue and the amino residue of the bovine serum albumin. BioGlue also adheres to the synthetic matrix material by a mechanical interlocking mechanism in the space of graft matrix.
Traditional Surgical Repair
Traditional surgical repair as determined by the surgeon
Beijing Anzhen Hospital, Capital Medical University, Beijing
Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing
Nanjing First Hospital, Nanjing
Changhai Hospital,The Second Military Medical University, Shanghai
Zhongshan Hospital, Fudan University, Shanghai
Wuhan Asia Heart Hospital, Wuhan
Henan Provincial People's Hospital, Zhengzhou
Lead Sponsor
CryoLife, Inc.
INDUSTRY