Lactobacillus Reuteri for Treatment of Uncomplicated UTI in Pregnant Women

NACompletedINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

December 15, 2017

Primary Completion Date

December 30, 2018

Study Completion Date

June 18, 2019

Conditions
Urinary Tract Infection in Pregnancy
Interventions
DIETARY_SUPPLEMENT

Probiotics

The Probiotic group will receive Sachet 1 - contains an instant cranberry drink, consisting of xylitol, monosodium citrate, cranberry aroma, cranberry extract, grape-skin extract, xanthan gum, acesulfame potassium and zinc gluconate and Sachet 2 - contains a total of 5\*10\^8 CFU of Lactobacillus reuteri DSM 16666/ATCC 55845 \& Lactobacillus reuteri DSM 17938, mixed with maltodextrin. Both Sachets should be administered Day 1-14, twice per day This group will also receive for Placebo for Antibiotic treatment day 1-7, twice per day

DRUG

Antibiotics

Patient in this group will receive for 7 days Amoxicillin + clavulanic acid (500 mg twice daily) for seven days in patients with negative nitrites in dipstick or oral nitrofurantoin (200mg twice per day) for patients with positive nitrates in dipstick. This group will also receive for placebo for probiotics 2 sachets for 14 days

Trial Locations (1)

14080

Hospital General Dr. Manuel Gea Gonzalez, Mexico City

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

BioGaia AB

INDUSTRY

lead

Innovacion y Desarrollo de Estrategias en Salud

OTHER

NCT03362697 - Lactobacillus Reuteri for Treatment of Uncomplicated UTI in Pregnant Women | Biotech Hunter | Biotech Hunter