Study of Emicizumab Prophylaxis in Participants With Hemophilia A With or Without Inhibitors Undergoing Minor Surgical Procedures

PHASE4TerminatedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

June 28, 2018

Primary Completion Date

March 13, 2020

Study Completion Date

March 13, 2020

Conditions
Hemophilia A
Interventions
DRUG

Emicizumab

Emicizumab via SC injection at a loading dose 3 mg/kg once weekly for the first 4 weeks, followed by 1.5 mg/kg once weekly, or by any other approved maintenance regimen, as long as the participant continues to derive sufficient benefit. Dosing was to be adjusted if the participant had a significant change in body weight.

Trial Locations (8)

14209

State University of New York at Buffalo; Women's and Children's Hospital of Buffalo, Buffalo

32607

University of Florida, Gainesville

46260

Indiana Hemophilia & Thrombosis center, Indianapolis

76104

Cook Childrens Medical Center, Fort Worth

84132

University of Utah; Division of Gastroenterology/Hepatology, Salt Lake City

90027

Childrens Hospital of LA, Los Angeles

94304

Stanford University/Lucile Packard Children's Hospital, Palo Alto

07112

Newark Beth Israel Medical Center, Newark

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Genentech, Inc.

INDUSTRY

NCT03361137 - Study of Emicizumab Prophylaxis in Participants With Hemophilia A With or Without Inhibitors Undergoing Minor Surgical Procedures | Biotech Hunter | Biotech Hunter