28
Participants
Start Date
November 20, 2017
Primary Completion Date
November 30, 2025
Study Completion Date
November 30, 2025
rituximab
rituximab 375 mg/m2 on days -11 and -4, The second dose of rituximab (day -4) is administered 7 days after the first dose (day -11), +/- 1 day. Rituximab may be administered by a local oncologist. If the participant has a CD20 negative tumor, rituximab can be omitted from the conditioning regimen.
bendamustine
bendamustine 160 mg/m2 intravenously on days -3 and -2
melphalan
melphalan 140 mg/m2 intravenously on day -1 before the reinfusion of autologous stem cells on day 0.
Autologous Stem Cell Transplantation (ASCT)
reinfusion of autologous stem cells on day 0.
Memorial Sloan Kettering Cancer Center, New York
Memorial Sloan Kettering Cancer Center
OTHER