Bilateral Orthotopic Lung Transplant - Bone Marrow Transplant

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

5

Participants

Timeline

Start Date

December 1, 2017

Primary Completion Date

March 1, 2024

Study Completion Date

March 1, 2024

Conditions
Primary ImmunodeficiencyPID
Interventions
BIOLOGICAL

CD3/CD19 neg allogeneic BMT

Negative selection for CD3/CD19 will be performed on a CliniMACS® depletion device within 36 hours of collection, and cryopreserved for later marrow transplantation. BMT conditioning and transplantation will start at least 8 weeks or more post lung transplant - once the participant is clinically judged suitable to undergo BMT conditioning and transplantion.

Trial Locations (1)

15224

Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

University of Pittsburgh

OTHER

collaborator

PPD Development, LP

INDUSTRY

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT03330795 - Bilateral Orthotopic Lung Transplant - Bone Marrow Transplant | Biotech Hunter | Biotech Hunter