Adjunct Photodynamic Therapy in Chronic Periodontitis Among Cigarette-smokers.

NACompletedINTERVENTIONAL
Enrollment

83

Participants

Timeline

Start Date

February 16, 2016

Primary Completion Date

July 2, 2017

Study Completion Date

September 16, 2017

Conditions
Chronic PeriodontitisSmoking
Interventions
DEVICE

Photodynamic therapy

In groups 1 and 2, aPDT was performed after SRP. The protocol for aPDT is described elsewhere. Briefly, using a blunt needle, 0.005% of Methylene blue was applied into the periodontal pocket and left in place for 10 seconds. The dye was then irradiated with a diode laser (670 nanometers) at 150 milliwatts. In each dye filled periodontal pocket, laser irradiation was performed for one minute using a flexible tip. In the present study, aPDT was performed once, at baseline, by a trained dentist.

PROCEDURE

Scaling and root planing (SRP)

In both groups, SRP was performed in one session under local anesthesia using handheld Gracey curettes No. 5/6. One trained dental hygienist blinded to the study groups and subgroups made 9 to 10 strokes in a vertical (apico-coronal) direction and the inclination between scaler tips and roots was maintained as zero. When the curved explorer indicated a smooth and hard dental surface, SRP was judged as completed. In all individuals, SRP was done in one session without any assigned time limit for completion.

All Listed Sponsors
lead

King Saud University

OTHER

NCT03308019 - Adjunct Photodynamic Therapy in Chronic Periodontitis Among Cigarette-smokers. | Biotech Hunter | Biotech Hunter