Alcohol Drinkers' Exposure to Preventive Therapy for TB (ADEPTT)

PHASE4CompletedINTERVENTIONAL
Enrollment

302

Participants

Timeline

Start Date

April 7, 2017

Primary Completion Date

April 1, 2021

Study Completion Date

April 1, 2021

Conditions
TuberculosisHIV/AIDSAlcohol Abuse
Interventions
DRUG

Isoniazid 300 Mg ORAL TABLET

The study intervention will include a single arm given (1) 6H: 300 mg INH daily by mouth for 6 months.

DRUG

Pyridoxine 25 Mg Oral Tablet

All participants will also receive 25 mg pyridoxine (vitamin B-6) daily by mouth for 6 months for the treatment duration to reduce the risk of INH-induced peripheral neuropathy.

Trial Locations (1)

Unknown

Mbarara University of Science and Technology/Mbarara Regional Referral Hospital, Mbarara

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Boston University

OTHER

collaborator

Boston Medical Center

OTHER

collaborator

Mbarara University of Science and Technology

OTHER

lead

University of California, San Francisco

OTHER