The Effects of the Female Hormones on Cerebral Perfusion

RecruitingOBSERVATIONAL
Enrollment

62

Participants

Timeline

Start Date

October 3, 2016

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2027

Conditions
Cerebral PerfusionContraceptionMenstrual Cycle
Interventions
DEVICE

MRI scan

Several MRI scan modalities: MPRAGE (structural scan), arterial spin labeling (cerebral perfusion), resting state functional-MRI (fMRI, cerebral activity) and diffusion MRI (white matter diffusion and white matter tracts).

DEVICE

Physiological monitoring

During MRI: heart rate, end-tidal carbon dioxide (CO2), respiratory rate and skin conductance

BIOLOGICAL

Blood sample

Blood sample after MRI-session: measurement of hematocrit, hemoglobin, estradiol, progesterone, follicle stimulation hormone and luteinizing hormone.

DEVICE

Blood pressure measurement

Measuring blood pressure before and after MRI-scan

DEVICE

Body temperature

Measuring body temperature before and after MRI-scan

OTHER

Questionnaires

Questionnaires at the start of the study on lifestyle. Additionally, a questionnaire before each scan session on the actual state of the volunteer (e.g. mood, caffeine consumption, alcohol, medication, etc.)

DIAGNOSTIC_TEST

Pregnancy test

Test for pregnancy using a pregnancy dipstick test

Trial Locations (1)

9000

RECRUITING

Ghent University Hospital, Ghent

All Listed Sponsors
lead

University Ghent

OTHER