21
Participants
Start Date
November 27, 2017
Primary Completion Date
October 30, 2020
Study Completion Date
March 7, 2022
Nivolumab Injection
2 possible doses : flat dose 240 mg q2 weeks or 1mg/kg q2 weeks
Cisplatin
40 mg/m2, once a week during radiotherapy
radiotherapy
"Intensity-modulated radiation therapy (including volumetric-modulated arc therapy and tomography) will be used. A dose of 45 Gy will be delivered to the pelvis in 25 fractions of 1.8 Gy using a 6-MV photon energy.~An additional dose of 54 Gy in 25 fractions of 2.16 Gy may be delivered to invaded lymph nodes using SIB-IMRT.~An additional lateral pelvic dose may be delivered if coverage of the target volumes is judged insufficient. The volumes, doses and techniques will be those usually used in each center."
Institut Curie Hopital René Huguenin, Saint-Cloud
Institut Curie, Paris
Hopital Européen Georges Pompidou, Paris
Collaborators (1)
Bristol-Myers Squibb
INDUSTRY
Institut Curie
OTHER