Follow-up Study After ACLSCT for Restoration of Corneal Epithelium in Patients With LSCD Due to Ocular Burns

CompletedOBSERVATIONAL
Enrollment

47

Participants

Timeline

Start Date

December 13, 2017

Primary Completion Date

March 31, 2023

Study Completion Date

March 31, 2023

Conditions
Limbal Stem Cell Deficiency Due to Ocular Burn
Interventions
PROCEDURE

Ophthalmologic examinations

epithelial defects assessment by fluorescein staining; superficial corneal neo-vascularization assessment; ocular tonometry; slit lamp examination; conjunctival (both bulbar and limbal) inflammation assessment; corneal sensitivity; central cornea involvement (for opacity or central CNV); Best-Corrected Visual Acuity; evaluation of symptoms.

OTHER

Digital pictures

Digital pictures 2D to be taken at each visit

OTHER

QoL Questionnaires

Quality of Life (NEI VFQ 25 and EQ-5D-3L/Y) questionnaires will be submitted at each visit

Trial Locations (1)

20100

Hospital San Raffaele, Milan

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Cromsource

INDUSTRY

lead

Holostem s.r.l.

INDUSTRY

NCT03288844 - Follow-up Study After ACLSCT for Restoration of Corneal Epithelium in Patients With LSCD Due to Ocular Burns | Biotech Hunter | Biotech Hunter