NCT03281902View on ClinicalTrials.gov

Genetic Analysis in Blood and Tumor Samples From Patients With Advanced or Metastatic Estrogen Receptor Positive and HER2 Negative Breast Cancer Receiving Palbociclib and Endocrine Therapy

Active, not recruitingOBSERVATIONAL
Enrollment

68

Participants

Timeline

Start Date

November 13, 2017

Primary Completion Date

March 4, 2026

Study Completion Date

March 4, 2026

Conditions
Advanced Breast CarcinomaLocally Advanced Breast CarcinomaMetastatic Breast CarcinomaRecurrent Breast CarcinomaStage III Breast Cancer AJCC v7Stage IIIA Breast Cancer AJCC v7Stage IIIB Breast Cancer AJCC v7Stage IIIC Breast Cancer AJCC v7Stage IV Breast Cancer AJCC v6 and v7
Interventions
PROCEDURE

Biopsy

Undergo tumor biopsy

PROCEDURE

Biospecimen Collection

Undergo collection of blood, urine, stool, and saliva

OTHER

Laboratory Biomarker Analysis

Correlative studies

Trial Locations (3)

55905

Mayo Clinic in Rochester, Rochester

85259

Mayo Clinic in Arizona, Scottsdale

32224-9980

Mayo Clinic in Florida, Jacksonville

Sponsors

Lead Sponsor

Mayo Clinic
All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Mayo Clinic

OTHER