NCT03277638View on ClinicalTrials.gov

Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM)

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

November 29, 2017

Primary Completion Date

December 31, 2025

Study Completion Date

June 30, 2026

Conditions
Glioblastoma, Adult
Interventions
DRUG

Pembrolizumab at 7 days prior

Pembrolizumab injections 7 days before surgery

DRUG

Pembrolizumab at 14 days post

Pembrolizumab injections 14 days after surgery

DRUG

Pembrolizumab at 35 days post

Pembrolizumab injections 35 days after surgery

PROCEDURE

Laser Interstitial Thermotherapy

surgical procedure to heat hard to reach tumors with a laser beam

Trial Locations (1)

44106

RECRUITING

University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center, Cleveland

All Listed Sponsors
lead

Case Comprehensive Cancer Center

OTHER