Multinational Clinical Study Comparing Isatuximab, Carfilzomib And Dexamethasone To Carfilzomib And Dexamethasone In Relapse And/Or Refractory Multiple Myeloma Patients

PHASE3CompletedINTERVENTIONAL
Enrollment

302

Participants

Timeline

Start Date

October 25, 2017

Primary Completion Date

January 14, 2022

Study Completion Date

January 3, 2025

Conditions
Plasma Cell Myeloma
Interventions
DRUG

isatuximab SAR650984

"Pharmaceutical form: solution for infusion~Route of administration: intravenous"

DRUG

carfilzomib

"Pharmaceutical form: solution for infusion~Route of administration: intravenous"

DRUG

dexamethasone

"Pharmaceutical form: tablets or solution for infusion~Route of administration: oral or intravenous"

Trial Locations (70)

1083

Investigational Site Number : 3480003, Budapest

1097

Investigational Site Number : 3480001, Budapest

1125

Investigational Site Number : 3480004, Budapest

1640

Investigational Site Number : 5540001, Auckland

2148

Investigational Site Number : 0360005, Blacktown

2485

Investigational Site Number : 0360006, Tweed Heads

2500

Investigational Site Number : 0360002, Wollongong

3065

Investigational Site Number : 0360001, Fitzroy

3081

Investigational Site Number : 0360004, Heidelberg West

6005

Investigational Site Number : 0360008, West Perth

6009

Investigational Site Number : 0360007, Nedlands

6021

Investigational Site Number : 5540002, Wellington

7400

Investigational Site Number : 3480005, Kaposvár

10126

Investigational Site Number : 3800002, Torino

10676

Investigational Site Number : 3000002, Athens

11527

Investigational Site Number : 3000005, Athens

11528

Investigational Site Number : 3000001, Athens

12808

Investigational Site Number : 2030001, Prague

16059

Investigational Site Number : 7920005, Bursa

26504

Investigational Site Number : 3000004, Pátrai

28041

Investigational Site Number : 7240003, Madrid

33600

Investigational Site Number : 2500002, Pessac

34381

Investigational Site Number : 7920002, Istanbul

40138

Investigational Site Number : 3800003, Bologna

41013

Investigational Site Number : 7240004, Seville

42123

Investigational Site Number : 3800004, Reggio Emilia

44093

Investigational Site Number : 2500001, Nantes

46017

Investigational Site Number : 7240002, Valencia

55139

Investigational Site Number : 7920004, Samsun

56126

Investigational Site Number : 3800001, Pisa

57010

Investigational Site Number : 3000003, Thessaloniki

59037

Investigational Site Number : 2500003, Lille

62500

Investigational Site Number : 2030002, Brno

69495

Investigational Site Number : 2500005, Pierre-Bénite

70852

Investigational Site Number : 2030003, Ostrava - Poruba

75012

Investigational Site Number : 2500006, Paris

77900

Investigational Site Number : 2030004, Olomouc

86021

Investigational Site Number : 2500004, Poitiers

94117

UCSF MS Center Site Number : 8400002, San Francisco

610027

Investigational Site Number : 6430003, Kirov

620102

Investigational Site Number : 6430002, Yekaterinburg

630047

Investigational Site Number : 6430004, Novosibirsk

29303-3040

Spartanburg Medical Center Site Number : 8400003, Spartanburg

41253-900

Hospital Sao Rafael - Rede D'OR Sao Luiz Site Number : 0760005, Salvador

90110-270

Hospital Mae de Deus Site Number : 0760003, Porto Alegre

14784-400

Hospital de Amor - Hospital do Cancer de Barretos - Fundacao Pio XII Site Number : 0760001, Barretos

05403-000

Hospital das Clinicas de Sao Paulo Site Number : 0760002, São Paulo

22775-002

Instituto COI de Educacao e Pesquisa Site Number : 0760004, Rio de Janeiro

V3V 1Z2

Investigational Site Number : 1240003, Surrey

E2L 4L2

Investigational Site Number : 1240001, Saint John

H1T 2M4

Investigational Site Number : 1240002, Montreal

028-3695

Investigational Site Number : 3920005, Shiwa-gun

860-8556

Investigational Site Number : 3920007, Kumamoto

392-8510

Investigational Site Number : 3920001, Suwa-shi

411-8777

Investigational Site Number : 3920003, Sunto-gun

150-8935

Investigational Site Number : 3920004, Shibuya-ku

162-8666

Investigational Site Number : 3920006, Shinjuku-ku

990-9585

Investigational Site Number : 3920002, Yamagata

602-715

Investigational Site Number : 4100006, Busan

06351

Investigational Site Number : 4100002, Gangnam-gu

03080

Investigational Site Number : 4100001, Seoul

03722

Investigational Site Number : 4100004, Seoul

06591

Investigational Site Number : 4100005, Seoul

08916

Investigational Site Number : 7240001, Badalona

08036

Investigational Site Number : 7240005, Barcelona

01250

Investigational Site Number : 7920003, Adana

06500

Investigational Site Number : 7920001, Ankara

PL6 8DH

Investigational Site Number : 8260004, Plymouth

LE1 5WW

Investigational Site Number : 8260005, Leicester

BS2 8ED

Investigational Site Number : 8260001, Bristol

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Sanofi

INDUSTRY

NCT03275285 - Multinational Clinical Study Comparing Isatuximab, Carfilzomib And Dexamethasone To Carfilzomib And Dexamethasone In Relapse And/Or Refractory Multiple Myeloma Patients | Biotech Hunter | Biotech Hunter