Dose-Escalation Study of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma (R/R MM)

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

420

Participants

Timeline

Start Date

September 19, 2017

Primary Completion Date

April 30, 2026

Study Completion Date

April 30, 2026

Conditions
Multiple Myeloma
Interventions
DRUG

Cevostamab

Cevostamab will be administered intravenously on a 21-day cycle, up to a total of 17 cycles.

DRUG

Tocilizumab

Tocilizumab will be administered as premedication during Cycle 1.

Trial Locations (17)

3004

Alfred Hospital, Melbourne

3022

Peter MacCallum Cancer Center, East Melbourne

10065

Memorial Sloan Kettering, New York

10128

Mount Sinai Hospital, New York

19104

University of Pennsylvania, Philadelphia

31008

Clinica Universidad de Navarra, Pamplona/iruña

35249

University of Alabama at Birmingham, Birmingham

37007

Hospital Clinico Universitario de Salamanca, Salamanca

37203

Tennessee Oncology - Nashville, Nashville

80045

University of Colorado Denver, Aurora

85259

Mayo Clinic Hospital - Arizona, Scottsdale

91010

City of Hope, Duarte

02215

Dana Farber Cancer Institute, Boston

77030-4009

The University of Texas MD Anderson Cancer Center, Houston

T2N 2T9

University of Calgary, Calgary

M5G 2M9

Princess Margaret Cancer Center, Toronto

H3T 1E2

Jewish General Hospital, Montreal

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Genentech, Inc.

INDUSTRY