A Study to Assess Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Fibrosis at Risk for Pulmonary Hypertension

PHASE3TerminatedINTERVENTIONAL
Enrollment

145

Participants

Timeline

Start Date

December 14, 2020

Primary Completion Date

June 9, 2023

Study Completion Date

June 30, 2023

Conditions
Pulmonary FibrosisPulmonary Hypertension
Interventions
COMBINATION_PRODUCT

INOpulse®

Subjects will be treated by means of an INOpulse® device using an INOpulse® nasal cannula.

COMBINATION_PRODUCT

Placebo

Subjects will be treated by means of an INOpulse® device using an INOpulse® nasal cannula.

COMBINATION_PRODUCT

Open Label Extension

Subjects will be treated by means of an INOpulse® device using an INOpulse® nasal cannula.

Trial Locations (64)

10016

NYU Langone, New York

10029

Mount Sinai Hospital, New York

10065

Weill Cornell Medical Center, New York

11794

Stony Brook University Hospital, Stony Brook

15123

University of Pittsburgh, Pittsburgh

19017

Thomas Jefferson University Korman Respiratory Institute, Philadelphia

19104

University of Pennsylvania, Philadelphia

19140

Temple University, Philadelphia

20007

Georgetown University, Washington D.C.

21205

Johns Hopkins Hospital, Baltimore

22042

Inova Heart and Vascular Institute Advanced Lung Disease Clinic, Falls Church

23229

Pulmonary Associates of Richmond, Richmond

27403

Pulmonix, LLC/LeBauer Cone Health, Greensboro

27517

The University of North Carolina at Chapel Hill Marsico Clinical Research Center, Chapel Hill

29425

Medical University of South Carolina, Charleston

29621

AnMed Health, Anderson

30106

Piedmont Healthcare, Austell

30322

Emory University, Atlanta

30342

Northside Hospital, Atlanta

32503

Avanza Medical Research Center, Pensacola

33125

University of Miami, Miami

33331

Cleveland Clinic, Weston

33470

Advanced Pulmonary Research Institute, Loxahatchee Groves

33612

University of South Florida, Tampa

33765

St. Francis Sleep Allergy and Lung Institute, Clearwater

35294

University of Alabama, Birmingham

37232

Vanderbilt University Medical Center, Nashville

40202

Norton Pulmonary Specialists, Louisville

University of Louisville, Louisville

43210

The Ohio State University, Columbus

44106

University Hospitals, Cleveland

45267

University of Cincinnati, Cincinnati

46260

Ascension St. Vincent Hospital, Indianapolis

48109

University of Michigan, Ann Arbor

48202

Henry Ford Hospital, Detroit

60153

Loyola University, Maywood

60201

North Shore University Hospital, Evanston

60611

Northwestern, Chicago

63017

The Lung Research Center, LLC, Chesterfield

68124

Creighton University, Omaha

75069

Metroplex Pulmonary and Sleep, McKinney

75246

Baylor University Medical Center, Dallas

75390

UT Southwestern Medical Center, Dallas

77030

University of Texas Health Science Center at Houston, Houston

80046

UC Denver Anschutz Medical Center, Aurora

80206

National Jewish, Denver

84108

University of Utah Health Sciences, Salt Lake City

85006

Banner - University Medical Center Arizona, Phoenix

85012

Arizona Pulmonary Specialists, Ltd., Phoenix

90024

University of California, Los Angeles

91324

Amicis Research, Northridge

92675

Paloma Medical Group, Paloma

93701

University of California San Francisco, Fresno

94305

Stanford University Medical Center, Stanford

95817

University of California Davis Health, Sacramento

97220

The Oregon Clinic, Portland

98195

University of Washington Medical Center, Seattle

62702 / 62794

Southern Illinois University, Springfield

02111

Tufts Medical Center, Boston

02115

Brigham and Women's Hospital, Boston

07901

Atlantic Health Respiratory Institute, Summit

V5Z 1M9

University of British Columbia, Vancouver

K7L 5G2

Queen's University/Hotel Dieu Hospital, Kingston

K7L 2V6

London Health Sciences Centre, London

Sponsors
All Listed Sponsors
lead

Bellerophon Pulse Technologies

INDUSTRY