Study of LAU-7b in the Treatment of Cystic Fibrosis in Adults

PHASE2CompletedINTERVENTIONAL
Enrollment

166

Participants

Timeline

Start Date

November 5, 2018

Primary Completion Date

September 15, 2021

Study Completion Date

September 15, 2021

Conditions
Cystic Fibrosis
Interventions
DRUG

LAU-7b

LAU-7b will be administered orally once-a-day with the first meal of the day as cycles of 21 days on, 7 days off, for a total of 6 planned cycles.

DRUG

Placebo oral capsule

Placebo will be administered orally once-a-day with the first meal of the day as cycles of 21 days on, 7 days off, for a total of 6 planned cycles.

Trial Locations (40)

2050

Department of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney

2145

Department of Respiratory and Sleep Medicine, Westmead Hospital, Westmead

2305

Respiratory Medicine, John Hunter Hospital, New Lambton Heights

3004

The Alfred Hospital, Melbourne

3168

Monash Lung and Sleep, Monash Health, Clayton

4101

Mater Misericordiae Ltd, Brisbane

6009

Institute of Respiratory Health, Harry Perkins Institute, Nedlands

12208

Albany Medical College, Albany

15224

Children's Hospital of Pittsburgh of UPMC, Pittsburgh

20010

Children's National Medical Center, Washington D.C.

23298

Virginia Commonwealth University, Richmond

29425

Medical University of South Carolina, Charleston

32603

Avanza Medical Research Center, Pensacola

32610

Division of pulmonary, critical care and sleep medicine, University of Florida, Gainesville

33021

Memorial Healthcare System, Joe DiMaggio Children's Hospital Cystic Fibrosis & Pulmonary Center, Hollywood

43205

Nationwide Children's Hospital, Columbus

44106

University Hospitals Cleveland Medical Center, Rainbow Babies and Children's Hospital, Cleveland

46202

Riley Hospital for Children, Indianapolis

48109

University of Michigan Health System, Ann Arbor

48201

Wayne State University, Harper University Hospital, Detroit

53226

Medical College of Wisconsin, Div of Pulmonary and Critical Care Medicine, Milwaukee

55455

The Minnesota Cystic Fibrosis Center, University of Minnesota, Minneapolis

63110

Washington University Medical School, St Louis

66103

University of Kansas Medical Center, Kansas City

73104

University of Oklahoma Health Sciences Center, Oklahoma City

83712

St-Luke's CF Center of Idaho, Boise

84132

University of Utah, Salt Lake City

90227

Children's Hospital Los Angeles, Los Angeles

90806

Long Beach Memorial Medical Center, Long Beach

95817

UC Davis Medical Center, Division of Pulmonary & Critical Care Medicine, Sacramento

97239

Cystic Fibrosis Center, Doernbecher Children's Hospital, Oregon Health & Science University, Portland

04102

Maine Medical Center Cystic Fibrosis Research, Portland

07962

Morristown Medical Center, NJ Adult Cystic Fibrosis Center, Morristown

08901

Rutgers University Clinical Research Center, RW Johnson University Hospital, New Brunswick

V6Z 1Y6

Pacific Lung Research Institute at St. Paul's Hospital, Vancouver

K1H 8L6

The Ottawa Hospital Center for Practice-Changing Research, Ottawa

G7H 5H6

Centre d'études cliniques CIUSS SLJ, Hôpital Chicoutimi, Chicoutimi

H2X2P1

Centre Hospitalier de l'Université de Montréal, Montreal

H4A 3J1

McGill University Health Center, Montreal

G1V 4G5

Centre de recherche de l'institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec

Sponsors
All Listed Sponsors
collaborator

Cystic Fibrosis Foundation

OTHER

lead

Laurent Pharmaceuticals Inc.

INDUSTRY