Study of Olaparib Maintenance Following Cabazitaxel-Carbo in Men With AVPC

25mg/m2 administered intravenously over 60 minutes on day 1 of cycles 1-6; given before carboplatin.

AUC 4 administered intravenously over 60 minutes on day 1 of cycles 1-6

5 mg administered by mouth twice daily on days 1-21 of cycles 1-6.

Administered by mouth twice daily at a dose of 300 mg by mouth twice daily, dispensed on Day 1 of cycle 7 to participants randomized to receive olaparib maintenance and every 21 days thereafter until the participant completes the study, withdraws from the study or the closure of the study.