Cardiovagal Baroreflex Deficits Impair Neurovascular Coupling and Cognition in POTS

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

51

Participants

Timeline

Start Date

July 1, 2017

Primary Completion Date

June 1, 2022

Study Completion Date

June 1, 2022

Conditions
Postural Orthostatic Tachycardia Syndrome (POTS)POTSOrthostatic Intolerance
Interventions
DRUG

Pyridostigmine

60mg by mouth

DRUG

Digoxin

0.5 (500mcg) by mouth

DRUG

Placebo

Lactulose 50mg by mouth

Trial Locations (1)

10532

New York Medical College/Bradhurst building, Hawthorne

Sponsors
All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

lead

New York Medical College

OTHER