40
Participants
Start Date
October 31, 2000
Primary Completion Date
March 31, 2003
Study Completion Date
March 31, 2003
Metformin
Metformin 850 mg x 1 per day for the first week, and 850 mg x 2 per day for the rest of the study period.. Orally. From inclusion (before gestational week 8) to delivery. Verbal and written diet and lifestyle advices at inclusion to the study. In addition 1 mg tablet of folate and one daily multivitamin tablet.
Placebo
Placebo, 2 tablets x 1 daily for the first week, and 2 tablets x 2 for the rest of the study period.Orally. From inclusion (that is before gestational week 12) to delivery. Verbal and written diet and lifestyle advices at inclusion to the study. In addition 1 mg tablet of folate and one daily multivitamin tablet.
Departments of Obstetrics and Gynecology and Endocrinology, St. Olav's Hospital, Trondheim
St. Olavs Hospital
OTHER
Norwegian University of Science and Technology
OTHER