Guanfacine Extended Release and Mindfulness Skills Therapy

PHASE4WithdrawnINTERVENTIONAL
0
Timeline

Start Date

March 1, 2019

Primary Completion Date

December 3, 2019

Study Completion Date

December 3, 2019

Conditions
Stress Disorder
Interventions
DRUG

Guanfacine Extended Release

Intuniv (guanfacine) is a prescription medicine used to treat attention deficit hyperactivity disorder (ADHD) in children who are at least 6 years old. An open-label trail of guanfacine extended release (GXR 1-4 mg/daily; Intuniv™) suggested benefits in improving behavioral and emotional regulation in children and adolescents with symptoms of traumatic stress. However, to date no controlled clinical trial has been completed assessing the effects of GXR on traumatic stress symptoms in youths

BEHAVIORAL

Mindfulness Skills Therapy

Mindfulness is a therapy for anxiety and stress. Mindfulness forms of therapy involve regulation of attention, maintaining it in immediate experience, regardless of the valence and desirability of the experience. To reduce anxiety, Mindfulness encourages observing and accepting anxiety-related thoughts

DRUG

Placebo

Placebo oral capsule

Trial Locations (1)

06030

UConn Health, Farmington

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Shire

INDUSTRY

collaborator

Yale University

OTHER

lead

UConn Health

OTHER

NCT03258476 - Guanfacine Extended Release and Mindfulness Skills Therapy | Biotech Hunter | Biotech Hunter