A Study to Evaluate eFT508 Alone and in Combination With Avelumab in Subjects With MSS Colorectal Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

56

Participants

Timeline

Start Date

September 18, 2017

Primary Completion Date

March 26, 2019

Study Completion Date

May 13, 2019

Conditions
Microsatellite Stable Relapsed or Refractory Colorectal Cancer
Interventions
DRUG

eFT508

eFT508 will be taken orally (PO) twice a day (bid).

DRUG

Avelumab

Avelumab 10 mg/kg will be administered intravenously (IV) on Day 1 and once every 2 weeks (q2wk) thereafter

Trial Locations (7)

34232

Florida Cancer Specialists, Sarasota

37203

Tennessee Oncology, Nashville

55905

Mayo Clinic, Rochester

64131

Kansas City Research Institute, Kansas City

77030

MD Anderson Cancer Center, Houston

80218

Sarah Cannon Research Institute at HealthONE, Denver

85259

Mayo Clinic, Scottsdale

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Merck KGaA, Darmstadt, Germany

INDUSTRY

collaborator

Pfizer

INDUSTRY

lead

Effector Therapeutics

INDUSTRY