Duloxetine and Dexamethasone for Improving Postoperative Pain

PHASE4CompletedINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

December 31, 2014

Primary Completion Date

January 31, 2016

Study Completion Date

January 31, 2016

Conditions
Post Operative Pain Control
Interventions
DRUG

Dulox capsule (60mg)

each patient received Dulox capsule (60mg) orally with sips of water 2 hours preoperatively and 100 ml 0.9% sodium chloride solution (NS) intravenous infusion (IVI) over 15 min

DRUG

combined Dulox capsule (60 mg) orally and Dex 0.1mg/kg diluted in 100 ml 0.9% NS IVI

each patient received combined Dulox capsule (60 mg) orally with sips of water and Dex 0.1mg/kg diluted in 100 ml 0.9% NS IVI over 15 min, 2 hours preoperatively

DRUG

a placebo capsule identical to Dulox capsule and 100 ml 0.9% NS IVI over 15 min, as a placebo for dexamethasone

each patient received a placebo capsule identical to Dulox capsule and 100 ml 0.9% NS IVI over 15 min, as a placebo for dexamethasone 2 hours preoperatively.

All Listed Sponsors
lead

Ain Shams University

OTHER

NCT03250494 - Duloxetine and Dexamethasone for Improving Postoperative Pain | Biotech Hunter | Biotech Hunter