SC IL-1Ra in SAH - Phase III Trial (SCIL)

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

612

Participants

Timeline

Start Date

October 11, 2018

Primary Completion Date

April 30, 2024

Study Completion Date

September 30, 2024

Conditions
Subarachnoid Hemorrhage
Interventions
DRUG

IL-1Ra

Doses to be administered subcutaneously (SC) twice daily (12 hourly) starting within 72 hours of ictus (onset of symptoms) for a maximum of 21 days from ictus (or sooner if discharged from neurosurgical centre).

DRUG

IL-1Ra Placebo

Doses to be administered subcutaneously (SC) twice daily (12 hourly) starting within 72 hours of ictus (onset of symptoms) for a maximum of 21 days from ictus (or sooner if discharged from neurosurgical centre).

Trial Locations (17)

PL6 8DH

Derriford Hospital, Plymouth

S10 2JF

Royal Hallamshire Hospital, Sheffield

CF14 4XW

University Hospital of Wales, Cardiff

LS1 3EX

Leeds General Infirmary, Leeds

BN2 5BE

Royal Sussex County Hospital, Brighton

BS10 5NB

Southmead Hospital, Bristol

CB2 0QQ

Addenbrookes Hospital, Cambridge

L9 7LJ

The Walton Centre, Liverpool

E1 1FR

Royal London Hospital, London

SW17 0QT

St George's Hospital, London

W6 8RF

Charing Cross Hospital, London

WC1N 3BG

National Hospital for Neurology and Neurosurgery, Queen Square, London

Unknown

Northern Care Alliance NHS Foundation Trust, Manchester

NG7 2UH

Queens Medical Centre, Nottingham

PR2 9HT

Royal Preston Hospital, Preston

SO16 6YD

Southampton General Hospital, Southampton

ST4 6QG

Royal Stoke University Hospital, Stoke-on-Trent

Sponsors
All Listed Sponsors
collaborator

National Institute for Health Research, United Kingdom

OTHER_GOV

collaborator

Clinical Trials Unit, Manchester

OTHER

collaborator

Northern Care Alliance NHS Foundation Trust

OTHER

lead

University of Manchester

OTHER

NCT03249207 - SC IL-1Ra in SAH - Phase III Trial (SCIL) | Biotech Hunter | Biotech Hunter