Nivolumab Plus Rituximab in First-line Follicular Lymphoma gr 1-3A

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

39

Participants

Timeline

Start Date

September 7, 2017

Primary Completion Date

May 11, 2022

Study Completion Date

June 30, 2027

Conditions
Follicular Lymphoma
Interventions
DRUG

Opdivo

"All patients will receive:~Nivolumab 240mg IV q2-weekly for four cycles~Patients in complete remission (CR):~Nivolumab 240mg IV q2-weekly for four further cycles (8 in total)~Patients with partial response (PR), stable disease (SD), asymptomatic or minor progressive disease (PD) post 4cycles receive:~Nivolumab 240mg IV plus rituximab 375mg/m2 IV q2-weekly for four cycles~Patients in CR:~Nivolumab 240mg IV q2-weekly for four further cycles (8 in total)~Patients with PR, SD, asymptomatic or minor PD post 4 cycles receive:~Nivolumab 240mg IV plus rituximab 375mg/m2 IV q2-weekly for four cycles"

Trial Locations (5)

3084

Austin Health, Heidelberg

3128

Eastern Health, Box Hill

Unknown

Ballarat Health, Ballarat

Monash Health, Clayton

St Vincent's Hospital, Melbourne

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

lead

Dr. Eliza Hawkes

OTHER_GOV

NCT03245021 - Nivolumab Plus Rituximab in First-line Follicular Lymphoma gr 1-3A | Biotech Hunter | Biotech Hunter