Food Effect, Oral & Intravenous Pharmacokinetics and Absolute Bioavailability of BAY1834845 Including Drug-drug Interaction With Methotrexate

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

August 18, 2017

Primary Completion Date

January 22, 2018

Study Completion Date

July 20, 2018

Conditions

Inflammation

Interventions

DRUG

BAY1834845

Single oral dose (IR \[immediate release\] tablets)

DRUG

BAY1834845

I.v. infusion of \[13C6\]-labeled BAY1834845

DRUG

Methotrexate

Single dose of commercially available MTX

Trial Locations (1)

PRAHealthSciences, Groningen