"Low-dose IL-2 in Established T1D - The PROREG Study"

PHASE1/PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

June 30, 2023

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2028

Conditions
Diabetes Mellitus, Type 1DiabetesDiabetes, Autoimmune
Interventions
BIOLOGICAL

ILT-101 (Aldesleukin; IL-2)

Administration of Low-Dose Interleukin-2 (ILT-101) for two years

OTHER

Treatment-Placebo Arm

Administration of Low-Dose Interleukin-2 (ILT-101) for one year, and then placebo for the second year.

OTHER

Placebo Arm

Participants in this group will receive a placebo injection for two years.

Trial Locations (1)

33136

Diabetes Research Institute, University of Miami Miller School of Medicine, Miami

All Listed Sponsors
collaborator

Diabetes Research Institute Foundation

OTHER

collaborator

University of Florida

OTHER

collaborator

University of California, San Francisco

OTHER

lead

Jay S. Skyler

OTHER