Left Atrial Cryoablation Enhanced by Ganglionated Plexi Ablation in the Treatment of Atrial Fibrillation

NACompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

July 1, 2012

Primary Completion Date

January 31, 2016

Study Completion Date

February 28, 2016

Conditions
Mitral Valve DiseaseCoronary Artery DiseaseTricuspid Valve DiseaseAortic Valve DiseaseAtrial Fibrillation
Interventions
PROCEDURE

Concomitant Mapping and Radiofrequency Ablation

"Mapping of GP around the orifice of pulmonary veins was performed, together with their radiofrequency ablation. In the area of right-side pulmonary veins, the procedure was performed prior to initiation of extracorporeal circulation. In case of the left-side PVs; the procedure was performed after initiation of extracorporeal circulation. Part of this procedure was also a decision and ablation of the ligament of Marshall.~GP mapping was performed using high-frequency stimulation (1000 beats min-¹, potential 18V, pulse width 1.5ms). The indication for GP ablation was a doubling in the R-R interval in the sinus rhythm, or ventricular rate slowing of more that 50% associated with a decrease of blood pressure\>20mmHg in patients with AF. In case of a positive response, radiofrequency ablation of the ganglia was performed following switching of the pen at the console. This procedure was repeated until the activity of the ganglia has disappeared."

PROCEDURE

No intervention

No intervention was performed in patients without ganglionated plexi.

All Listed Sponsors
lead

University Hospital Ostrava

OTHER

NCT03239262 - Left Atrial Cryoablation Enhanced by Ganglionated Plexi Ablation in the Treatment of Atrial Fibrillation | Biotech Hunter | Biotech Hunter