Deferiprone to Delay Dementia (The 3D Study)

PHASE2CompletedINTERVENTIONAL
Enrollment

81

Participants

Timeline

Start Date

January 19, 2018

Primary Completion Date

January 1, 2023

Study Completion Date

February 23, 2023

Conditions
Mild Cognitive ImpairmentProdromal Alzheimer's DiseaseMild Alzheimer's Disease
Interventions
DRUG

Deferiprone 600mg delayed release tablets

The active substance, Deferiprone, is a member of the 3-hydroxypyrid-4-one class of iron chelators, which have a high affinity for ferric iron, binding it in a 3:1 (Deferiprone:iron) molar ratio.

DRUG

Placebo Oral Tablet

The placebo will mimic the Deferiprone arm in every way, except the placebo will not include the active ingredient

Trial Locations (8)

2113

KaRa Institute of Neurological Diseases, Macquarie Park

2298

Hunter New England Local Health District, Waratah

3004

Alfred Hospital, Melbourne

3050

Royal Melbourne Hospital, Parkville

3084

Austin Health, Heidelberg

3128

Box Hill Hospital, Box Hill

3174

NeuroCentrix, Noble Park

6009

Australian Alzheimer's Research Foundation, Nedlands

Sponsors
All Listed Sponsors
collaborator

The Florey Institute of Neuroscience and Mental Health

OTHER

lead

Neuroscience Trials Australia

OTHER

NCT03234686 - Deferiprone to Delay Dementia (The 3D Study) | Biotech Hunter | Biotech Hunter