Dolutegravir Plus 2 NRTIs, in Treatment-Naïve HIV-2 Infected Subjects

PHASE2CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

April 5, 2017

Primary Completion Date

July 2, 2019

Study Completion Date

July 2, 2019

Conditions
HIV II Infection
Interventions
DRUG

Dolutegravir 50 mg

Dolutegravir will be used in combination with 2 nucleoside reverse transcriptase inhibitors (NRTIs). The NRTIs used in combination with DTG will be abacavir (ABC) plus lamivudine (3TC) or tenofovir (TDF) plus emtricitabine (FTC), which is in line with the current standard of care. The combination ABC/3TC/DTG will be preferential except in case of hepatitis B co-infection or in case the subject has a positive HLA-B\*5701 allele screening assessment.

Trial Locations (6)

Unknown

Centro Hospitalar de Lisboa Central Hospital Curry Cabral, Lisbon

Centro Hospitalar de Lisboa Ocidental Hospital de Egas Moniz, Lisbon

Centro Hospitalar Lisboa Norte Hospital de Santa Maria, Lisbon

Hospital Beatriz Ângelo Loures, Lisbon

Hospital Garcia de Orta, Lisbon

Hospital Professor Doutor Fernando Fonseca Amadora, Lisbon

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Blueclinical, Ltd.

OTHER

NCT03224338 - Dolutegravir Plus 2 NRTIs, in Treatment-Naïve HIV-2 Infected Subjects | Biotech Hunter | Biotech Hunter