A Study to Evaluate the Efficacy and Safety of Glecaprevir/Pibrentasvir (ABT-493/ABT-530) in Treatment-Naive and Treatment-Experienced, Non-Cirrhotic Asian Adults With Chronic Hepatitis C Virus Genotype (GT) 1 to GT6 Infection With or Without Human Immunodeficiency Virus Co-Infection

PHASE3CompletedINTERVENTIONAL
Enrollment

546

Participants

Timeline

Start Date

October 4, 2017

Primary Completion Date

October 18, 2018

Study Completion Date

February 15, 2019

Conditions
Hepatitis C Virus (HCV)
Interventions
DRUG

Placebo

Matching placebo tablet for oral administration

DRUG

Glecaprevir/Pibrentasvir

Coformulated tablet for oral administration

Trial Locations (48)

13620

Seoul National Univ Bundang ho /ID# 163367, Seongnam

22332

Inha University Hospital /ID# 163320, Junggu

47392

Inje University Busan Paik Hospital /ID# 163329, Pusan

50612

Pusan Nat Univ Yangsan Hosp /ID# 163334, Yangsan

100015

Beijing Di Tan Hospital, Capital Medical University /ID# 156847, Beijing

100034

1st Hospital of Peking Uni /ID# 156845, Beijing

100039

302 Military Hospital Of China /ID# 156841, Beijing

100044

Peking University Peoples Hospit /ID# 156846, Beijing

100050

Beijing Friendship Hospital /ID# 156840, Beijing

100069

Beijing Youan Hosp, Cap Med Un /ID# 163430, Beijing

110004

Shengjing Hospital of China Medical University /ID# 156824, Shenyang

110006

The Sixth People's Hospital of Shenyang /ID# 156849, Shenyang

116031

Dalian Sixth Peoples Hospital /ID# 163433, Dalian

119228

National University Hospital ( /ID# 163272, Singapore

130021

The First Hosp of Jilin Univ /ID# 156820, Changchun

169608

Singapore General Hospital /ID# 163271, Singapore

200003

Shanghai Changzheng Hospital /ID# 158072, Shanghai

200025

Ruijin Hospital, Shanghai Jiaotong /ID# 157336, Shanghai

200040

Huashan Hospital of Fudan University /ID# 156904, Shanghai

201508

Shanghai Public Health Cli Ctr /ID# 156832, Shanghai

210002

Chinese People's Liberation Army 81 Hospital /ID# 156862, Nanjing

210003

The Second Hospital of Nanjing /ID# 156863, Nanjing

210029

Jiangsu Province People's Hospital /ID# 156861, Nanjing

250021

Jinan Infectious Diseases Hosp /ID# 156886, Jinan, Shandong

300170

Tianjin Third Central Hospital /ID# 156816, Tianjin

350025

Mengchao Hepatobiliary Hospita /ID# 156902, Fuzhou

400038

1st Affiliated Hosp 3rd Milita /ID# 156831, Chongqing

410008

Xiangya Hospital Central South University /ID# 156901, Changsha

430022

Union Hospital Tongji Medical College Huazhong University of Science and Technol /ID# 156884, Wuhan

430030

Tongji Hosp Tongji Med College /ID# 156885, Wuhan

450000

Henan Provincial Peoples Hosp /ID# 157197, Zhengzhou, Henan

510060

Guangzhou Eighth People's Hosp /ID# 156859, Guangzhou

510080

Guangdong General Hospital /ID# 156822, Guangzhou

510515

Nanfang Hospital of Southern Medical University /ID# 156860, Guangzhou

510630

The Third Affiliated Hospital Of Sun Yat-Sen University /ID# 156900, Guangzhou

529889

Changi General Hospital /ID# 163270, Singapore

570311

Hainan General Hospital /ID# 156839, Haikou, Hainan

610041

West China Hospital /ID# 156830, Chengdu

710038

Fourth Military Medical University Tangdu Hospital, PLA /ID# 156765, Xi'an

710061

First Affiliated Hospital of Medical College of Xi'an Jiaotong University /ID# 163432, Xi'an

830054

1st Aff Hosp Xinjiang Med Uni /ID# 156887, Ürümqi

602-739

Pusan National University Hosp /ID# 163371, Busan

03722

Yonsei University Health System, Severance Hospital /ID# 163339, Seodaemun-gu

06351

Samsung Medical Center /ID# 163364, Seoul

06591

Cath Univ Seoul St Mary's Hosp /ID# 163341, Seoul

08308

Korea Universtiy Guro Hospital /ID# 163380, Seoul

03080

Seoul National University Hospital /ID# 163348, Seoul

05505

Asan Medical Center /ID# 163336, Seoul

Sponsors

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INDUSTRY