Multi-Dimensional Diagnosis,Individualized Therapy,and Management Technique for Major Depressive Disorder:Based on Clinical and Pathological Characteristics

Fluoxetine is one kind of selective serotonin reuptake inhibitor(SSRIs), whose effect is much better than other non-underload subtypes compared with underload subtypes.So patients would be treated with fluoxetine only.

the investigators would recommend fluoxetine to help to cure depressive disorder.And CBT is a very effective way for patients to alleviate or relieve clinical symptoms during episode stage.

Amfebutamone is one kind of SNRIs, and it shows much better therapy effect on patients with exhaustion /dizziness.So the investigators recommend these two drugs to help to cure patients with depressive disorder.

the investigators recommend drug(fluoxetine and amfebutamone) and physical treatment as intervention.

Fluvoxamine could inhibit CYP1A2 and CYP2C19 and affect the metabolism of melatonin, and help to release symptoms of depressive disorder with sleep problems.

the investigators recommend lithium as a mood stabilizer and use fluvoxamine to affect the level of melatonin.

the investigators recommend depressants and mood stabilizers as well as physical therapy to help to cure depressive disorder.

the investigators recommend behavioral therapy as well as drugs.

Mirtazapine is one kind of antagonist of a2 adrenergic receptors and could block 5-hydroxytryptamine2 and 5-hydroxytryptamine3,help to release symptoms like anxiety or somatization.Besides, SNRIs could also make similar effect on patients.Therefore, the investigators recommend mirtazapine/SNRIs to treat patients with depressive disorder.

the investigators recommend CBT and mirtazapine as interventions.The dosage and frequency would depend on patients' severity of symptoms .

the investigator recommend mirtazapine and SNRIs to treat patients with major depressive disorder.

the investigators would manage to use drugs and physical treatment to help to release the symptoms of depressive disorder.

patients in this group would receive therapy strategies according to their symptoms and preference.