RAI Plus Immunotherapy for Recurrent/Metastatic Thyroid Cancers

EARLY_PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

11

Participants

Timeline

Start Date

July 10, 2017

Primary Completion Date

February 6, 2023

Study Completion Date

July 31, 2026

Conditions
Thyroid Cancer
Interventions
DRUG

Durvalumab (Medi4736)

durvalumab 1500 mg IV every 4 weeks

RADIATION

Radioiodine (RAI)

100 mCi (+/- 10 mCi) of 131I will be administered a day after Thyrogen injections have been administered for two consecutive calendar days.

Trial Locations (7)

10065

Memorial Sloan Kettering Cancer Center, New York

10604

Memorial Sloan Kettering Westchester, Harrison

11553

Memorial Sloan Kettering Nassau, Uniondale

11725

Memorial Sloan Kettering Commack, Commack

07920

Memorial Sloan Kettering Basking Ridge, Basking Ridge

07748

Memorial Sloan Kettering Monmouth, Middletown

07645

Memorial Sloan Kettering Bergen, Montvale

Sponsors

Collaborators (2)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

collaborator

MedImmune LLC

INDUSTRY

lead

Memorial Sloan Kettering Cancer Center

OTHER