Study of Brentuximab Vedotin Plus TAK228 for Relapsed/Refractory Classical Hodgkin Lymphoma, Anaplastic Large Cell Lymphoma and Other CD30+Peripheral T-Cell Lymphomas

PHASE1WithdrawnINTERVENTIONAL
0
Timeline

Start Date

March 31, 2018

Primary Completion Date

March 31, 2021

Study Completion Date

March 31, 2021

Conditions
Malignant Neoplasms Stated as Primary Lymphoid HaematopoieticClassical Hodgkin LymphomaAnaplastic Large Cell LymphomaCD30+ Peripheral T-cell Lymphoma
Interventions
DRUG

Brentuximab Vedotin

1.8 mg/kg by vein on Day 1 per cycle by vein over about 30 minutes on Day 1 of each cycle.

DRUG

TAK228

Starting Dose and Schedule of TAK228: 2 mg by mouth, 5 days on and 2 days off per week with repeated weekly cycles. The study doctor will tell participant how often to take the study drug.

DEVICE

Glucose Monitor

Participant monitors glucose (sugar) levels at home with a glucose monitor during the first 2 months participant is taking the study drug.

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Takeda

INDUSTRY

lead

M.D. Anderson Cancer Center

OTHER