PSMA PET Imaging of Recurrent Prostate Cancer

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

1,171

Participants

Timeline

Start Date

June 26, 2017

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2026

Conditions
Prostate AdenocarcinomaProstate Cancer
Interventions
DRUG

Ga-HBED-iPSMA PET

Patients will be injected with 100-300 MBq of 68Ga-HBED-iPSMA and after a waiting of 60-90 minutes patients will be scanned from mid-skull to mid-thigh.

DIAGNOSTIC_TEST

PET/CT

PET/CT will be acquired using a GE 710 or 690 time-of-flight PET/CT scanner. Following a waiting period of 60-90 minutes post 68Ga-HBED-iPSMA administration, patients will be scanned from top of the skull to mid-thigh. Images will be acquired with patients in a supine position with their arms raised above their head. If patients cannot raise their arms above the head, the arms will be comfortably positioned and secured by the side of the patient. The PET may be combined with a CT scan as a PET/CT or a MRI scan as PET/MR.

DIAGNOSTIC_TEST

MRI

Patients may undergo a diagnostic MRI of the prostate, other body parts or a whole-body MRI at the same imaging session as clinically indicated.

Trial Locations (7)

10065

Memorial Sloan Kettering Cancer Center, New York

10604

Memorial Sloan Kettering Westchester (Consent only), Harrison

11553

Memorial Sloan Kettering Nassau (Consent only), Uniondale

11725

Memorial Sloan Kettering Commack (Consent only), Commack

07920

Memorial Sloan Kettering Basking Ridge (Consent only), Basking Ridge

07748

Memorial Sloan Kettering Monmouth (Consent only), Middletown

07645

Memorial Sloan Kettering Bergen (Consent only ), Montvale

All Listed Sponsors
lead

Memorial Sloan Kettering Cancer Center

OTHER