Clinical Trial of Neoadjuvant Targeted Treatment to NSCLC Patients

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

590

Participants

Timeline

Start Date

September 30, 2017

Primary Completion Date

January 31, 2026

Study Completion Date

January 31, 2026

Conditions
2-year Disease-Free Survival
Interventions
DRUG

Oral Navelbine + Carboplatin

The patient will be given Navelbine 60 mg/m2, p.o. day 1 and 8 of every cycle (21 days) plus carboplatin AUC 5, i.v. day 1 of every cycle.After 2 cycle we will evaluate their clinical response.Then operable patients will have surgery.

DRUG

Gefitinib

The patient will be given Gefitinib 250mg,p.o.,q.d. for 8 weeks.After 8 weeks we evaluate their clinical response.Then operable patients will have surgery.

Trial Locations (5)

510000

Sun Yat-sen University Cancer Center, Guangzhou

The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou

518000

Shenzhen People's Hospital, Shenzhen

523000

Dongguan People's Hospital, Dongguan

525000

Maoming Affiliated Hospital of Southern Medical University, Maoming

All Listed Sponsors
collaborator

Shenzhen People's Hospital

OTHER

collaborator

Dongguan People's Hospital

OTHER_GOV

collaborator

Sixth Affiliated Hospital, Sun Yat-sen University

OTHER

collaborator

Maoming Affiliated Hospital of Southern Medical University

UNKNOWN

lead

Sun Yat-sen University

OTHER