22
Participants
Start Date
September 18, 2017
Primary Completion Date
December 20, 2019
Study Completion Date
December 20, 2019
IMA970A plus CV8102 and Cyclophosphamide
"Study treatment starts with a single intravenous infusion of 300mg/m2 Cyclophosphamide.~Three days later patients start vaccination therapy with IMA970A plus CV8102 Each vaccination consists of a dose of 6.80 milligrams (mg) IMA970A (containing approx. 400 micrograms \[µg\] of each individual peptide) followed by a dose of 50 µg CV8102. First IMA970A is injected intradermally (i.d.) and about 10 minutes later CV8102 is injected i.d. at the same vaccination site in close proximity. Patients will receive 4 vaccinations at weekly intervals followed by 5 vaccinations at 3-weekly intervals for a total duration of about 4.5 months."
Universitair Ziekenhuis Antwerpen (UZA), Division of Gastroenterology and Hepatology, Edegem
Universidad de Navarra (NAVAR), Internal Medicine, Pamplona
Ospedale Sacro Cuore-Don Calabria U.O.C. Oncologica Medica, Negrar
Universitätsklinik für Allgemeine, Viszeral- und Transplantationschirurgie, Tübingen
"Istituto Nazionale Tumori Pascale (INTNA)", Napoli
The University of Birmingham, School of Immunity and Infection, College of Medical and Dental Science (BHAM), Birmingham
Collaborators (2)
Immatics Biotechnologies GmbH
INDUSTRY
CureVac
INDUSTRY
European Commission
OTHER
National Cancer Institute, Naples
OTHER