A Study to Determine the Abuse Potential of Tozadenant Relative to D-Amphetamine and Placebo When Administered Orally in Healthy, Non-Dependent, Recreational Polydrug Users

PHASE1TerminatedINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

September 18, 2017

Primary Completion Date

November 28, 2017

Study Completion Date

November 28, 2017

Conditions
Abuse Potential
Interventions
DRUG

Tozadenant

2, 4, 6 or 8 Tozadenant 60 mg tablets

DRUG

Placebo oral tablet

2, 4, 6 or 8 Tozadenant matching placebo tablets

DRUG

d-amphetamine

2 or 4 capsules, each containing 2 over-encapsulated d-amphetamine 5 mg tablets

DRUG

Placebo oral capsule

2 or 4 capsules, each containing d-amphetamine matching over-encapsulated PLACEBO 200 mg lactose tablet

Trial Locations (1)

M5V 2T3

INC Research Toronto, Inc., Toronto

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Acorda Therapeutics

INDUSTRY

lead

Biotie Therapies Inc.

INDUSTRY