The Effect of On-line Hemodiafiltratrion on Nutritional Status and Body Composition

NACompletedINTERVENTIONAL
Enrollment

33

Participants

Timeline

Start Date

April 1, 2012

Primary Completion Date

March 31, 2013

Study Completion Date

March 31, 2013

Conditions
Chronic Kidney Disease Requiring Chronic Dialysis
Interventions
DEVICE

High-flux hemodialysis

Hemodialysis treatment thrice weekly with the high-flux FX-100 dialyzer (Fresenius Medical Care, Bad Homburg, Germany; membrane: Helixone®; surface: 2.2 m2; UF coefficient: 73 ml/h mm Hg; ß2-microglobulin-sieving coefficient: 0.8; albumin-sieving coefficient: 0.001), including a minimum target dialysis dose (Kt/Vurea) ≥1.2 and a session length of 3.0 to 6.0 h. Hemodialysis treatments were performed with the 5008 hemodialysis system (Fresenius Medical Care).

DEVICE

On line-hemodiafiltration

Post-dilution on line-hemodiafiltration treatment thrice weekly with the high-flux FX-100 dialyzer (Fresenius Medical Care, Bad Homburg, Germany; membrane: Helixone®; surface: 2.2 m2; UF coefficient: 73 ml/h mm Hg; ß2-microglobulin-sieving coefficient: 0.8; albumin-sieving coefficient: 0.001), including a minimum target dialysis dose (Kt/Vurea) ≥1.2 and a session length of 3.0 to 6.0 h. Post-dilution on line-hemodiafiltration treatments were performed with the 5008 hemodialysis system (Fresenius Medical Care), with automatic adjustment of the substitution fluid flow rate for maximising substitution volume while simultaneously avoiding haemoconcentration and filter clotting.

All Listed Sponsors
lead

Pablo Molina

OTHER

NCT03190629 - The Effect of On-line Hemodiafiltratrion on Nutritional Status and Body Composition | Biotech Hunter | Biotech Hunter