MUK Nine b: OPTIMUM Treatment Protocol

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

95

Participants

Timeline

Start Date

September 28, 2017

Primary Completion Date

October 1, 2025

Study Completion Date

May 31, 2026

Conditions
Multiple Myeloma
Interventions
DRUG

Cyclophosphamide

Chemotherapy

DRUG

Bortezomib

Chemotherapy

DRUG

Lenalidomide

Chemotherapy

DRUG

Daratumumab

Chemotherapy

DRUG

Dexamethasone

Chemotherapy

DRUG

Melphalan

Chemotherapy

DRUG

Filgrastim

Haematopoietic agent for the stem cell harvest

Trial Locations (21)

B15 2TH

Queen Elizabeth Hospital, Birmingham

Unknown

Birmingham Heartlands Hospital, Birmingham

Blackpool Victoria Hospital, Blackpool

Royal Bournemouth Hospital, Bournemouth

Bristol Haematology & Oncology Centre, Bristol

Beatson Oncology Centre, Glasgow

Kings College Hosptial, London

Manchester Royal Infirmary, Manchester

The Christie Hospital, Manchester

Norfolk and Norwich University Hospital, Norwich

Nottingham University Hosptial, Nottingham

Churchill Hospital, Oxford

Derriford Hospital, Plymouth

Royal Stoke Hospital, Stoke-on-Trent

BH7 7DW

Royal Hampshire County Hospital, Bournemouth

DD1 9SY

Ninewells Hospital, Dundee

NN16 8UZ

Kettering General Hosptial, Kettering

LE1 5WW

Leicester Royal Infirmary, Leicester

SO16 6YD

Southampton General Hospital, Southampton

SM2 5PT

Royal Marsden Hospital, Sutton

WR5 1DD

Worcester Royal Hospital, Worcester

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Myeloma UK

OTHER

collaborator

Celgene

INDUSTRY

collaborator

Janssen, LP

INDUSTRY

lead

University of Leeds

OTHER