Nivolumab Combined With Daratumumab With or Without Low-dose Cyclophosphamide

PHASE2CompletedINTERVENTIONAL
Enrollment

62

Participants

Timeline

Start Date

February 21, 2018

Primary Completion Date

January 25, 2023

Study Completion Date

January 25, 2024

Conditions
Myeloma
Interventions
DRUG

nivolumab-daratumumab

nivolumab-daratumumab will be given without low-dose cyclophosphamide until progression

DRUG

nivolumab-daratumumab with low-dose cyclophosphamide

nivolumab-daratumumab with low-dose cyclophosphamide will be given until progression

Trial Locations (9)

Unknown

Rijnstate ziekenhuis, Arnhem

Radboud MC, Nijmegen

MUMC, Maastricht

UMC Groningen, Groningen

Albert Schweitzer Ziekenhuis, Dordrecht

Meander MC, Amersfoort

St. Antonius Ziekenhuis, Nieuwegein

UMC Utrecht, Utrecht

1081HV

VU University Medical Center, Amsterdam

All Listed Sponsors
collaborator

Erasmus Medical Center

OTHER

collaborator

UMC Utrecht

OTHER

collaborator

Maastricht University Medical Center

OTHER

collaborator

Meander Medical Center

OTHER

collaborator

St. Antonius Hospital

OTHER

collaborator

Isala

OTHER

collaborator

Albert Schweitzer Hospital

OTHER

collaborator

Radboud University Medical Center

OTHER

collaborator

University Medical Center Groningen

OTHER

collaborator

Rijnstate Hospital

OTHER

lead

Amsterdam UMC, location VUmc

OTHER