Does Dapagliflozin Provide Additional Health Benefits To Dietary Counseling For Weight Loss?

PHASE2CompletedINTERVENTIONAL
Enrollment

62

Participants

Timeline

Start Date

May 3, 2017

Primary Completion Date

December 21, 2018

Study Completion Date

December 21, 2018

Conditions
Weight Loss
Interventions
DRUG

Dapagliflozin Tablet

Daily oral administration of dapagliflozin with dietary counseling to promote weight loss. Dapagliflozin 5 mg tablet will begin as one tablet per day for the first 14-days. In the absence of complications, side effects, or unfavorable reactions, the dose will then increase to two tablets for the remainder of the study.

DRUG

Placebo Tablet

Daily administration of placebo tablet with dietary counseling to promote weight loss. Matching placebo for dapagliflozin 5 mg tablet will begin as one tablet per day for the first 14-days. In the absence of complications, side effects, or unfavorable reactions, the dose will then increase to two tablets for the remainder of the study.

Trial Locations (1)

80523-1582

Colorado State University, Dept. of Health and Exercise Science, Fort Collins

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

Christopher Bell

OTHER