NCT03174041 - A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

April 18, 2017

Primary Completion Date

June 23, 2017

Study Completion Date

June 23, 2017

Conditions

Healthy Participants

Interventions

DRUG

Midazolam

Single dose midazolam

DRUG

GDC-0853

Multiple doses GDC-0853 for 6 days

DRUG

Midazolam and GDC-0853

Multiple doses GDC-0853 and single dose midazolam

DRUG

Rosuvastatin

Single dose rosuvastatin

DRUG

Rosuvastatin and GDC-0853

Multiple doses GDC-0853 and single dose rosuvastatin

DRUG

Simvastatin

Single dose simvastatin

DRUG

Simvastatin and GDC-0853

Multiple doses GDC-0853 and single dose simvastatin

DRUG

GDC-0853

Single dose GDC-0853

DRUG

Itraconazole

Multiple doses itraconazole for 6 days

DRUG

GDC-0853 and itraconazole

Multiple doses itraconazole and single dose GDC-0853

Trial Locations (3)

32117

Covance Research Unit - Daytona, Daytona Beach

47710

Covance Clinical Research Unit Inc.; Covance Gfi Research, Evansville

53704

Covance Clinical Research Unit, Inc, Madison