A Study of GDC-0853 in Participants With Refractory Chronic Spontaneous Urticaria (CSU).

PHASE2CompletedINTERVENTIONAL
Enrollment

134

Participants

Timeline

Start Date

May 26, 2017

Primary Completion Date

September 27, 2019

Study Completion Date

October 25, 2019

Conditions
Urticaria
Interventions
DRUG

GDC-0853

GDC-0853 will be administered orally at dosages of 50, 150 and 200mg to participants, as per the dosing schedules described above.

DRUG

Placebo

Matching Placebo will be administered orally, as per the dosing schedules described above.

Trial Locations (27)

10117

Charite Mitte; Klinik fur Dermatologie, Berlin

15831

Hautarztpraxis Mahlow, Mahlow

33165

New Horizon Research Center, Miami

34470

Renstar Medical Research, Ocala

35209

Clinical Research Center of Alabama, LLC, Birmingham

48419

Klinik für Haut- und Geschlechtskrankheiten, Universitätsklinikum Münster, Münster

55131

Universitätsmedizin Johannes Gutenberg Universität, Mainz

74136

Vital Prospects Clinical Research Institute PC - CRN, Tulsa

77433

Center for Clinical Studies, Cypress

85251

Allergy & Asthma Immunology Associates, Scottsdale

86179

Licca Clinical Research Institute, Augsburg

91786

Integrated Research of Inland, Upland

92506

Integrated Research Group Inc, Riverside

92691

Southern California Research Center, Mission Viejo

93301

Kern Allergy Med Clinic, Inc., Bakersfield

94063

Allergy & Asthma Consultants, Redwood City

02914

Asthma, Nasal Disease, and Allergy Research Center of New England, East Providence

05403

Timber Lane Allergy and Asthma Research, LLC, Burlington

V6T 1Z4

University of British Columbia, Vancouver

L8S 1G5

Private Practice - Dr. Jason Ohayon, Hamilton

L3P 1X2

Lynde Institute for Dermatology, Markham

L5A 3V4

Cheema Research, Mississauga

K1G 6C6

Yang Medicine, Ottawa

M4V 1R2

Gordon Sussman Clinical Research, Toronto

J2B 5L4

Private Practice - Dr. Isabelle Delorme, Drummondville

G1V 4M6

Centre de Recherche Applique En Allergie de Quebec, Québec

01307

Universitätsklinikum Carl Gustav Carus, Klinik und Poliklinik für Augenheilkunde, Dresden

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Genentech, Inc.

INDUSTRY